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Image Search Results
Journal: Journal of proteomics
Article Title: Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer
doi: 10.1016/j.jprot.2017.02.013
Figure Lengend Snippet: Sequence coverage obtained for different IgGs1 and IgG2 by top-down ETD Orbitrap FTMS. Indicated scans consist of 10 microscans each. Note, only c - and z -type ions were considered for ETD MS (for both “high-field” and “standard” Orbitrap data), whereas also b - and y -type ions were included in EThcD MS analysis.
Article Snippet: Visually, this is represented in through a color-coded map based on crystal structure of
Techniques: Sequencing
Journal: Journal of proteomics
Article Title: Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer
doi: 10.1016/j.jprot.2017.02.013
Figure Lengend Snippet: Product ion abundance analysis of ETD top-down MS of adalimumab with 10 ms ETD duration and trastuzumab with 10 and 25 ms duration. In the case of trastuzumab, the color-coded histogram demonstrates the improvement in sequence coverage obtained through the combination of 10 ms (magenta) and 25 ms (cyan) ETD MS/MS data. Whereas medium and large product ions (e.g., z117 and z63) are generally produced using 10 ms duration, smaller ions such as z16, z17 and z18 are detected only in the case of a longer ETD duration, presumably as the result of secondary fragmentation (i.e., re-fragmentation of larger product ions).
Article Snippet: Visually, this is represented in through a color-coded map based on crystal structure of
Techniques: Sequencing, Tandem Mass Spectroscopy, Produced
Journal: Journal of proteomics
Article Title: Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer
doi: 10.1016/j.jprot.2017.02.013
Figure Lengend Snippet: Color-coded representation of ETD PIA results for the C-terminus of the heavy chain of trastuzumab. (A) 10 ms ETD. (B) 25 ms ETD. The displayed image is based on X-ray crystallography data (PDB entry: 3D6G).
Article Snippet: Visually, this is represented in through a color-coded map based on crystal structure of
Techniques: